Source: Lancet Neurology
Area: News
The Lancet Neurology has featured a review on the diagnosis, disease course, and management of patients with Kleine-Levin syndrome.
 
Kleine-Levin syndrome is a rare sleep disorder that mainly affects adolescents and is characterised by relapsing-remitting episodes of severe hypersomnia, cognitive impairment, apathy, derealisation, and psychiatric and behavioural disturbances. Boys are more frequently affected than girls.
 
In terms of pharmacological management, the review suggests that amantadine at least once at the beginning of an episode can be considered to see whether the episode will abate. If patients experience intense anxious symptoms during episodes, sublingual bromazepam can be considered, and if delusions or behavioural d…

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